MDARD Michigan Core Pesticide Applicator Practice Exam

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For which class(es) of pesticides is cholinesterase monitoring appropriate?

  1. Organophosphate and carbamate insecticides

  2. Pyrethroids

  3. Phenoxy herbicides, such as 2,4-D

  4. Neonicotinoids

The correct answer is: Organophosphate and carbamate insecticides

Cholinesterase monitoring is specifically appropriate for organophosphate and carbamate insecticides due to their mode of action, which involves inhibiting the enzyme acetylcholinesterase. This enzyme is crucial for the proper functioning of the nervous system, as it breaks down the neurotransmitter acetylcholine in the synaptic cleft. When cholinesterase is inhibited, acetylcholine accumulates, leading to overstimulation of the nervous system, which can result in serious health effects for individuals who are exposed to these pesticides. Organophosphates and carbamates pose a particular risk of cholinesterase inhibition, making monitoring essential for individuals who may be exposed as part of their work. By conducting cholinesterase monitoring, health and safety protocols can help identify any early signs of potential poisoning, allowing for timely intervention and reducing health risks to applicators. Other classes of pesticides, such as pyrethroids, phenoxy herbicides, and neonicotinoids, do not primarily affect cholinesterase levels in the same manner as organophosphates and carbamates do. Therefore, monitoring for cholinesterase activity is not relevant for those pesticide classes.